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Updated: May 29, 2026

07:44
Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
Published on: July 6, 2016
Strand exchange reaction modulated fluorescence "off-on" switching of hybridized DNA duplex stabilized silver
Weiwei Guo1, Jipei Yuan, Erkang Wang
1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, PR China.
Abstract:
The fluorescence (FL)"off-on" switching of designed DNA duplex stabilized silver nanoclusters can be accomplished through the control of DNA strand exchange reaction. The successful sequential control of the FL emission of silver nanoclusters in "off-on" switching cycles confirms that the DNA duplex stabilized silver nanoclusters can work as a new kind of DNA FL switch.

