Related Experiment Video
Updated: May 29, 2026
09:36
Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
Published on: October 16, 2010
[Pregnancy and malignant diseases part I--general principles]
Akusherstvo I Ginekologiia
|September 16, 2011
Summary
Malignant diseases during pregnancy are rare but serious. Treatment prioritizes maternal health, fetal safety, and preserving reproductive potential, often involving surgery or chemotherapy after the first trimester.
Area of Science:
- Oncology
- Obstetrics & Gynecology
Context:
- Neoplastic diseases complicate 0.02-0.1% of pregnancies.
- Malignancies are a leading cause of death in women of reproductive age.
- Increasing maternal age and reproductive technologies may increase cancer incidence during pregnancy.
Purpose:
- To outline management strategies for neoplastic diseases in pregnant patients.
- To emphasize individualized treatment balancing maternal, fetal, and reproductive outcomes.
Summary:
- Treatment follows general standards but is individualized to protect the fetus and preserve fertility.
- Surgery and chemotherapy post-first trimester are generally safe for the fetus.
- Radiotherapy, particularly pelvic, is contraindicated during pregnancy; delivery decisions require a multidisciplinary team.
Impact:
- Appropriate management can prevent adverse fetal outcomes and preserve maternal reproductive capacity.
- Extending pregnancy to 35-37 weeks gestation is recommended to mitigate prematurity complications.
- Multidisciplinary consultation ensures optimal outcomes for mother and child.
Related Concept Videos
01:24Disorders of the Female Reproductive System
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
01:07Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
02:59Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
02:07Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
02:07Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
01:19Mitral Valve Prolapse III: Nursing Management
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...