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Related Concept Videos

Salivary Glands and Saliva01:23

Salivary Glands and Saliva

The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

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Published on: December 31, 2017

Saliva, diagnostics, and dentistry.

M S Urdea1, P D Neuwald, B L Greenberg

  • 1Halteres Associates LLC, 5858 Horton Street, Suite 280, Emeryville, CA 94608, USA.

Advances in Dental Research
|September 16, 2011
PubMed
Summary
This summary is machine-generated.

Saliva diagnostics offer a promising avenue for disease detection and health monitoring. This research highlights the potential of salivary diagnostics and the role of dental professionals in advancing this field.

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Area of Science:

  • Oral Health
  • Biomedical Diagnostics
  • Translational Research

Background:

  • Saliva is a well-established clinical entity in oral health.
  • Saliva is gaining national recognition for its diagnostic potential.
  • The National Institutes of Health (NIH) and the President's Office of Science and Technology have identified salivary diagnostics as a key area.

Purpose of the Study:

  • To explore the concept of high-impact diagnostics using saliva.
  • To define the role of dentists in the advancement of salivary diagnostics.
  • To examine the UK Biobank's potential impact on the clinical use of saliva.

Main Methods:

  • Review of national initiatives and reports (e.g., Grand Challenges, GPRA).
  • Discussion of the scientific foundation for salivary diagnostics.
  • Examination of existing and developing infrastructures for salivary diagnostics.

Main Results:

  • President Obama identified "Detecting dozens of diseases in a sample of saliva" as a Grand Challenge.
  • NIH's 2011 GPRA report included salivary diagnostics as a high-risk, long-term initiative.
  • The UK Biobank is being developed to impact translational and clinical applications of saliva.

Conclusions:

  • The scientific community, particularly oral health professionals, is called to advance salivary diagnostics.
  • There is a clear mandate to establish the efficacy of salivary diagnostics for health monitoring and disease diagnosis.
  • Infrastructure development, such as the UK Biobank, is crucial for realizing the clinical potential of saliva.