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Updated: May 29, 2026

Analysis of the Mitochondrial Density and Longitudinal Distribution in Rat Live-Skeletal Muscle Fibers by Confocal Microscopy
Published on: December 1, 2023
Endoplasmic reticulum stress in skeletal muscle: origin and metabolic consequences
Louise Deldicque1, Peter Hespel, Marc Francaux
1Research Centre for Exercise and Health, Department of Biomedical Kinesiology, K.U. Leuven, Belgium. louise.deldicque@faber.kuleuven.be
Abstract:
In secretory organs, such as the liver, the pancreas, and the adipose tissue, endoplasmic reticulum (ER) stress plays a key role in the etiology of cell disturbances implicated in many diseases. Although much less studied, ER stress also is present in skeletal muscle. In the present review, we hypothesize that ER stress may have important metabolic consequences in skeletal muscle. This review presents the situations in which ER stress is activated in skeletal muscle and its metabolic consequences.
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