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08:07
Preclinical Drug Testing in Scalable 3D Engineered Muscle Tissues
Published on: April 7, 2023
[Musculoskeletal adverse drug reactions]
1Clinique romande de réadaptation Suva-Care, Swiss Olympic Medical Center, Av. de Grand-Champsec 90, 1951 Sion. pierre-etienne.fournier@crr-suva.ch
Revue Medicale Suisse
|September 17, 2011
Summary
Musculoskeletal complaints are common and can stem from rheumatologic or endocrine diseases. Adverse drug reactions can also affect muscles and bones, typically resolving after medication cessation.
Area of Science:
- Rheumatology
- Endocrinology
- Pharmacology
Context:
- Musculoskeletal complaints are a frequent clinical presentation.
- Differential diagnoses include rheumatologic and endocrine disorders.
- Adverse drug reactions can manifest as musculoskeletal issues.
Purpose:
- To highlight the diverse etiologies of musculoskeletal complaints.
- To emphasize the role of medication side effects on the locomotor system.
- To outline diagnostic and management strategies.
Summary:
- Musculoskeletal issues frequently arise from various conditions, including rheumatologic and endocrine diseases.
- The locomotor system, encompassing muscles and bones, can be affected by adverse drug reactions, usually leading to temporary disability.
- Diagnosis relies on medical history, physical examination (locomotor and neurologic), and laboratory blood tests.
Impact:
- Improved diagnostic accuracy for musculoskeletal complaints.
- Enhanced recognition of drug-induced musculoskeletal conditions.
- Optimized patient management through targeted interventions.
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