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[Extrapulmonary lesions of sarcoidosis]
K Seki1, M Sakatani, T Tachibana
1Department of Internal Medicine, Kawanishi Municipal Hospital, Hyôgo, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi
|January 1, 1990
Summary
Extrapulmonary sarcoidosis, affecting organs beyond the lungs, is increasingly diagnosed in Japan. Hepatic lesions are crucial for diagnosing and monitoring sarcoidosis progression.
Area of Science:
- Pulmonology and Internal Medicine
- Diagnostic Imaging
- Pathology
Context:
- Sarcoidosis commonly presents with pulmonary involvement but frequently exhibits extrapulmonary manifestations.
- Recent years have seen increased detection of diverse extrapulmonary sarcoidosis lesions in Japan.
- Hepatic sarcoidosis is a significant finding, often identified irrespective of pulmonary stage.
Purpose:
- To document the range and diagnostic significance of extrapulmonary sarcoidosis lesions in Japan.
- To highlight the role of hepatic lesions in sarcoidosis diagnosis and management.
- To review modern diagnostic modalities for extrapulmonary sarcoidosis.
Summary:
- Extrapulmonary sarcoidosis lesions, including those in the heart, CNS, liver, and other organs, have been increasingly identified in Japan over the past decade.
- Hepatic lesions are frequently detected via peritoneoscopy and liver biopsy, proving vital for diagnosis and clinical course monitoring.
- Diagnostic tools such as CT, MRI, echography, and various scans aid in identifying these extrapulmonary manifestations.
Impact:
- Increased awareness and improved diagnostic strategies for extrapulmonary sarcoidosis.
- Better understanding of sarcoidosis progression and disability, particularly in older individuals.
- Potential for earlier intervention and management of sarcoidosis-related disabilities.