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[Multicystic kidney dysplasia].

F Krull1, P F Hoyer, R Habenicht

  • 1Abteilung für Pädiatrische Nephrologie, Medizinische Hochschule Hannover.

Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
|April 1, 1990
PubMed
Summary
This summary is machine-generated.

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Multicystic kidney dysplasia in children is often diagnosed prenatally or in early childhood. Prognosis is linked to co-occurring renal and other malformations.

Area of Science:

  • Pediatric Nephrology
  • Congenital Anomalies
  • Medical Imaging

Context:

  • Retrospective analysis of 48 children with multicystic kidney dysplasia (MKD) treated between 1976-1989.
  • MKD diagnosis occurred prenatally via ultrasound or postnatally up to 12 years of age.
  • No familial occurrence noted, but other renal diseases observed in 8 families.

Purpose:

  • To analyze the clinical course and outcomes of pediatric multicystic kidney dysplasia.
  • To identify presenting symptoms and associated malformations in children with MKD.
  • To evaluate the impact of associated conditions on patient prognosis.

Summary:

  • 48 children (27 boys, 21 girls) with MKD analyzed.
  • Presenting symptoms included abdominal mass, UTIs, and vomiting.

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  • Associated malformations found in 18 patients (cardiac, other kidney dysplasia, ureter obstruction).
  • Normal renal function (serum creatinine) and no hypertension in patients without associated kidney malformations.
  • 42 patients underwent surgical removal of the affected kidney.

    • Impact:

    • Highlights the importance of prenatal diagnosis and early detection of MKD.
    • Emphasizes the significant role of associated malformations in determining the prognosis of MKD.
    • Provides insights into the long-term clinical course and management of pediatric MKD.