Related Experiment Video
Updated: May 29, 2026
09:11
Genome Editing with CompoZr Custom Zinc Finger Nucleases (ZFNs)
Published on: June 14, 2012
Engineering zinc finger nucleases for targeted mutagenesis of zebrafish
Jeffry D Sander1, J-R Joanna Yeh, Randall T Peterson
1Molecular Pathology Unit, Center for Computational and Integrative Biology, and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Methods in Cell Biology
|September 20, 2011
Abstract:
Zinc finger nucleases provide an important platform for performing reverse genetics in zebrafish. Here we review various methods and resources that have been used to create customized zinc finger nucleases for use in zebrafish. We also provide a framework for choosing among the various publicly available platforms available to engineer ZFNs.
