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Updated: May 29, 2026
05:05
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Pemphigus treatment in Japan
Akiko Tanikawa1, Masayuki Amagai
1Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan. tanikawa@sc.itc.keio.ac.jp
Dermatologic Clinics
|September 20, 2011
Summary
Pemphigus is an autoimmune blistering disease affecting skin and mucous membranes. Systemic corticosteroids remain the primary treatment according to 2010 Japanese dermatology guidelines.
Area of Science:
- Dermatology
- Autoimmunology
- Pathophysiology
Background:
- Pemphigus encompasses autoimmune blistering conditions.
- Characterized by skin and mucous membrane lesions due to keratinocyte adhesion loss.
- Recent Japanese guidelines for pemphigus management were published in 2010.
Purpose of the Study:
- To summarize the 2010 Japanese guidelines for pemphigus management.
- To inform dermatologists about current pemphigus treatment standards.
Main Methods:
- Review of the 2010 Japanese guidelines for pemphigus.
- Focus on established treatment protocols for dermatologists.
Main Results:
- Systemic corticosteroids are identified as the gold standard treatment.
- Corticosteroids are the first-line therapy for pemphigus management.
Conclusions:
- The 2010 Japanese guidelines emphasize systemic corticosteroids for pemphigus.
- These guidelines provide a foundational approach for dermatologists treating pemphigus.
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