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Related Concept Videos

Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the exudate's...
Healing I: Introduction01:11

Healing I: Introduction

Healing is the physiological process by which the body restores the integrity and function of damaged tissues following injury. It involves a coordinated interplay of cellular proliferation, extracellular matrix remodeling, and growth factor signaling. The extent and nature of the tissue damage determine whether healing occurs by resolution, regeneration, or replacement.ResolutionResolution represents the most complete form of healing, occurring when the injury is minimal and tissue...
Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...

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Related Experiment Video

Updated: May 29, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
02:49

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

[Tissue expansion in burns sequelae].

M Mimoun1, D Boccara, M Chaouat

  • 1Service de chirurgie plastique, reconstructrice, esthétique, centre de brûlés, hôpital Saint-Louis, Assistance publique de Paris, université de Paris-VII, Paris-Diderot, 1, avenue Claude-Vellefaux, 75010 Paris, France. maurice.mimoun@rth.aphp.fr

Annales De Chirurgie Plastique Et Esthetique
|September 20, 2011
PubMed
Summary
This summary is machine-generated.

Skin expansion offers a revolutionary approach to repairing burn sequelae, enabling tissue replacement with high-quality grafts. This method addresses unique challenges like skin loss and expansion deficits for improved outcomes.

More Related Videos

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
14:14

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Published on: April 16, 2017

Related Experiment Videos

Last Updated: May 29, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
02:49

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
14:14

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Published on: April 16, 2017

Area of Science:

  • Plastic Surgery
  • Regenerative Medicine
  • Burn Reconstruction

Context:

  • Burn sequelae present significant reconstructive challenges.
  • Traditional methods often fall short in restoring tissue quality and function.
  • Skin expansion offers a promising alternative for complex burn reconstructions.

Purpose:

  • To detail the indications and surgical techniques for skin expansion in burn sequelae.
  • To highlight the unique challenges and complications associated with skin expansion in this context.
  • To provide insights into treatment planning and the long-term sustainability of expanded tissue.

Summary:

  • Skin expansion is a pivotal technique for burn sequelae repair, allowing for tissue replacement with grafts of comparable quality.
  • The authors discuss specific considerations for burns, including indications, surgical methods, and potential complications.
  • Key challenges addressed are the "invisible loss" of skin, mandatory expansion deficits, sub-scarring, treatment strategies, and long-term viability.

Impact:

  • Enhances reconstructive options for severe burn injuries.
  • Improves the quality and functionality of repaired tissues.
  • Offers a potential solution for achieving near-native tissue replacement in burn scar revision.