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Perioperative ketorolac use in children undergoing lower extremity osteotomies

Robert Michael Kay1, Michael Leathers, Michael P Directo

  • 1Children's Orthopaedic Center, Children's Hospital Los Angeles, CA 90027, USA. rkay@chla.usc.edu

Journal of Pediatric Orthopedics
|September 20, 2011
PubMed

Insights

Perioperative ketorolac use in pediatric lower extremity osteotomies showed no increased risk of osseous or soft tissue complications. This study supports the safety of ketorolac for pain management in pediatric orthopaedic surgery.

Area of Science:

  • Pediatric Orthopaedics
  • Pain Management
  • Surgical Complications

Background:

  • Ketorolac is effective for pediatric surgical pain relief.
  • Concerns exist regarding ketorolac's potential complications in pediatric orthopaedics, including nonunion, delayed union, and blood loss.
  • This study addresses these concerns by examining complications associated with perioperative ketorolac use.

Purpose of the Study:

  • To evaluate the safety and complication rates of perioperative ketorolac in children undergoing lower extremity osteotomies.
  • To compare outcomes between children who received ketorolac and those who did not.

Main Methods:

  • Retrospective review of 327 children undergoing osteotomy surgery with at least 6 months follow-up.
  • Comparison of complication rates (osseous, soft tissue, union, wound healing) between 299 patients receiving ketorolac and 28 not receiving ketorolac.
  • Analysis of estimated blood loss and transfusion requirements.

Main Results:

  • No significant differences in osseous or soft tissue complications between ketorolac and non-ketorolac groups.
  • Low rates of delayed union (0.7% overall) and wound complications (4.9% overall) with no significant group differences.
  • No significant difference in estimated blood loss or need for blood transfusion between groups.

Conclusions:

  • Perioperative ketorolac use in children undergoing lower extremity osteotomies is safe.
  • The study supports the use of ketorolac for pain management in this pediatric surgical population.
  • No increased risk of union or wound complications was observed.
Abstract

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