Related Experiment Video
Updated: May 29, 2026

A Model of Cardiac Remodeling Through Constriction of the Abdominal Aorta in Rats
Published on: December 2, 2016
[Hypertrophic cardiomyopathy with left ventricular aneurysm]
Ewelina Becherka1, Jarosław D Kasprzak, Jerzy Górny
1II Katedra Kardiologii, Uniwersytet Medyczny w Łodzi, Łódź. ebecherka@wp.pl
Insights
This case study highlights a 68-year-old woman with hypertrophic cardiomyopathy who developed dyspnea post-acute coronary syndrome. Echocardiography revealed left ventricular aneurysm and intraventricular gradients, indicating complex cardiac dynamics.
Area of Science:
- Cardiology
- Cardiac Imaging
- Cardiovascular Disease
Background:
- Hypertrophic cardiomyopathy (HCM) is a genetic heart muscle disease.
- Acute coronary syndrome (ACS) can precipitate or exacerbate cardiac complications.
- Left ventricular (LV) dysfunction requires careful diagnostic evaluation.
Observation:
- A 68-year-old woman with known HCM presented with progressive dyspnea following ACS.
- Echocardiography demonstrated hypertrophic hypertrophy and an apical LV aneurysm.
- Doppler-echocardiography identified midventricular and subaortic intra-LV gradients.
Findings:
- The patient exhibited significant intraventricular pressure gradients.
- Systolic anterior motion of the anterior mitral leaflet was observed.
- The combination of HCM, LV aneurysm, and intraventricular gradients presents a complex clinical scenario.
Implications:
- This case underscores the importance of comprehensive echocardiographic assessment in HCM patients with worsening symptoms after ACS.
- Understanding intraventricular gradients and LV aneurysm is crucial for managing dyspnea and preventing adverse outcomes.
- Further research may explore the specific mechanisms linking ACS, LV aneurysm formation, and gradient development in HCM.
Abstract:
We present a case of 68 year-old woman with previously diagnosed hypertrophic cardiomyopathy complaining of progressive dyspnoe after the acute coronary syndrome. The echocardiogram confirmed hypertrophic hypertrophy and revealed an aneurysm in the apical portion of the left ventricle (LV). The Doppler-echocardiography showed two intra-LV gradients: midventricular and subaortic, with systolic anterior motion of anterior mitral leaflet.
Related Concept Videos
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Mitral Regurgitation I: Introduction
Cardiomyopathy II: Dilated Cardiomyopathy
Heart Failure II: Pathophysiology
Aneurysm I: Introduction
Mitral Stenosis I: Introduction

