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Related Experiment Video

Updated: May 29, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Exercise and physical activity in mental disorders.

Elisabeth Wolff¹, Katharina Gaudlitz, Brigitt-Leila von Lindenberger

¹Klinik für Psychiatrie und Psychotherapie, Charité-Universitätsmedizin Berlin, Charité Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany. elisabeth.wolff@charite.de

European Archives of Psychiatry and Clinical Neuroscience

|September 22, 2011

Summary

Regular exercise and physical activity show therapeutic benefits for various mental health conditions, including anxiety, depression, and schizophrenia. More research is needed to fully understand these effects and optimize treatments.

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Area of Science:

Psychiatry
Exercise Science
Mental Health Research

Background:

Exercise and physical activity are recognized for their role in preventing and managing mental health disorders.
Despite decades of discussion, robust clinical trials investigating exercise as therapy are limited across many psychiatric conditions.

Purpose of the Study:

To review studies on exercise as a therapeutic intervention for anxiety disorders, affective disorders, eating disorders, schizophrenia, and substance use disorders.
To summarize the mechanisms underlying the therapeutic effects of exercise and physical activity.
To discuss implications for clinical practice and future research.

Main Methods:

Systematic review of randomized controlled trials and other relevant studies.
Analysis of research investigating exercise interventions in various psychiatric populations.
Synthesis of findings on both psychological and physiological mechanisms.

Main Results:

Evidence suggests disorder-specific benefits of exercise and physical activity in mental health.
Mechanisms include metabolic, physiological, and psychological factors.
Adequately powered randomized controlled trials remain sparse for many conditions.

Conclusions:

Exercise and physical activity offer promising therapeutic potential for a range of mental disorders.
Further high-quality research is crucial to establish exercise as a standard treatment.
Integrating exercise into therapeutic practice requires careful consideration of disorder-specific benefits.