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Updated: May 29, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Published on: October 12, 2018

Dermatopathic lymphadenitis in HIV.

H R Vanisri¹, N M Nandini, Sumeet Gujral

¹Department of Pathology, JSS Medical College, Mysore, India.

Indian Journal of Sexually Transmitted Diseases and AIDS

|September 23, 2011

Summary

This summary is machine-generated.

Dermatopathic lymphadenitis is a rare condition in Human immunodeficiency virus (HIV) positive individuals. This case highlights its presence even without visible skin issues, confirmed by lymph node biopsy and immunohistochemistry.

Keywords:

Dermatopathic lymphadenitis follicular dendritic cells human immunodeficiency virus immunohistochemistry

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Area of Science:

Immunopathology
Oncology
Infectious Diseases

Background:

Dermatopathic lymphadenitis is an uncommon condition often associated with various skin diseases.
Its occurrence in Human immunodeficiency virus (HIV) infection is rare and can present diagnostic challenges.
Early and accurate diagnosis is crucial for patient management.

Observation:

A 50-year-old female, diagnosed as HIV positive, presented with lymphadenopathy.
No overt dermatological conditions were noted at the time of presentation.
Fine needle aspiration cytology revealed a lymphoproliferative lesion.

Findings:

Lymph node biopsy confirmed atypical lymphoid proliferation with a prominent T-zone.
Immunohistochemistry results were consistent with dermatopathic lymphadenitis.
The findings underscore the importance of considering this diagnosis in HIV-positive individuals.

Implications:

This case expands the understanding of dermatopathic lymphadenitis in the context of HIV infection.
It emphasizes the need for thorough investigation of lymphadenopathy in HIV patients, even in the absence of skin lesions.
Further research may elucidate the specific mechanisms linking HIV and this condition.