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Updated: May 29, 2026
10:49
Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
Changing patterns of rotavirus genotypes in Turkey.
Anil Tapisiz1, Zeynep Ceren Karahan, Ergin Çiftçi
1Department of Pediatric Infectious Disease, Ankara University Medical School, 06100 Dikimevi, Ankara, Turkey. anilaktas@gazi.edu.tr
Current Microbiology
|September 23, 2011
Summary
This study identified G9P[8] as the most common human rotavirus genotype in Turkish children, highlighting the need for ongoing surveillance before vaccine introduction. The findings reveal significant shifts in rotavirus genotype distribution.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Rotavirus infection causes significant mortality in children, particularly in Europe.
- Understanding rotavirus genotype circulation is crucial for effective public health strategies and vaccine implementation.
Purpose of the Study:
- To describe the circulation dynamics of human rotavirus genotypes in Turkey.
- To analyze epidemiological changes in rotavirus infections among children under 5 years old.
Main Methods:
- Multiplex reverse transcription polymerase-chain reaction (RT-PCR) was used for rotavirus genotyping.
- Stool samples from 100 rotavirus-positive children under 5 were analyzed.
Main Results:
- G9 and P[8] were the most frequent G and P genotypes, respectively.
- G9P[8] was the predominant circulating genotype (19%), followed by G1P[8] and G4P[6].
- A high incidence of mixed rotavirus infections (26%) and detection of novel/reassortant strains were observed.
Conclusions:
- Rotavirus genotype distribution in Turkey shows distinct and changing patterns.
- Continuous surveillance is essential for informing the national immunization program and rotavirus vaccine policy.
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