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Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

Radiological Investigation I: X-ray and CT

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

Radiation: Applications

Radiation: Applications

The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...

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Related Experiment Video

Updated: May 29, 2026

Mast Cells in the Microenvironment of Hepatocellular Carcinoma Confer Favorable Prognosis: A Retrospective Study using QuPath Image Analysis Software

Mast Cells in the Microenvironment of Hepatocellular Carcinoma Confer Favorable Prognosis: A Retrospective Study using QuPath Image Analysis Software

Published on: April 12, 2024

Next generation radiologic-pathologic correlation in oncology: Rad-Path 2.0.

Michael D Kuo¹, Shota Yamamoto

¹Department of Radiological Sciences, University of California, Los Angeles, David Geffen School of Medicine, 10833 Le Conte Ave, Los Angeles, CA 90095-1721, USA. michaelkuo@mednet.ucla.edu

AJR. American Journal of Roentgenology

|September 24, 2011

Summary

This summary is machine-generated.

Radiologic-pathologic (Rad-Path) correlation is evolving beyond traditional imaging to incorporate molecular insights. This shift, termed Rad-Path 2.0, integrates diverse diagnostic disciplines for future radiology success.

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Last Updated: May 29, 2026

Mast Cells in the Microenvironment of Hepatocellular Carcinoma Confer Favorable Prognosis: A Retrospective Study using QuPath Image Analysis Software

Mast Cells in the Microenvironment of Hepatocellular Carcinoma Confer Favorable Prognosis: A Retrospective Study using QuPath Image Analysis Software

Published on: April 12, 2024

Area of Science:

Radiology and Pathology
Oncology
Genomics

Background:

Classical radiologic-pathologic (Rad-Path) correlation links imaging to ex vivo findings.
Molecular biology advancements are challenging traditional diagnostic paradigms, especially in oncology.
Conventional imaging shows potential for revealing genomic disease properties.

Purpose of the Study:

To advocate for a paradigm shift in radiologic-pathologic correlation.
To introduce the concept of the next generation of Rad-Path correlation (Rad-Path 2.0).

Main Methods:

Review of current trends in diagnostic sciences.
Analysis of the impact of molecular assays and imaging.
Discussion of the integration of genomic information with diagnostic imaging.

Main Results:

The lines between diagnostic sciences are blurring.
New molecular imaging and in vitro diagnostic assays are emerging.
Conventional imaging offers insights into genomic disease characteristics.

Conclusions:

The future of radiology depends on technological progress.
Convergence of distinct diagnostic disciplines is essential for advancing Rad-Path correlation.