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05:35
A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
Anemia in children with down syndrome
Ariel Tenenbaum1, Sarah Malkiel, Isaiah D Wexler
1Department of Pediatrics, Hadassah University Medical Center, Mount Scopus Campus, Jerusalem, Israel.
International Journal of Pediatrics
|September 24, 2011
Summary
Children with Down syndrome have similar rates of anemia and iron deficiency as the general population. Early monitoring for these conditions is crucial for timely intervention and supporting cognitive development.
Area of Science:
- Pediatrics
- Genetics
- Hematology
Background:
- Iron deficiency anemia significantly affects cognitive development in children.
- Children with Down syndrome may be at increased risk for anemia and iron deficiency.
Purpose of the Study:
- To determine the prevalence of anemia and iron deficiency in children with Down syndrome.
- To identify risk factors associated with anemia in this population.
Main Methods:
- A prolective cross-sectional study was conducted at a multidisciplinary Down syndrome medical center.
- 149 children (aged 0-20 years) with Down syndrome were enrolled.
- Data included medical history, examinations, nutritional assessment, and blood tests.
Main Results:
- 8.1% of the children studied had anemia.
- 50.0% of children with iron studies showed iron deficiency.
- Arab ethnicity and low weight for age were significant risk factors for anemia.
Conclusions:
- Children with Down syndrome exhibit anemia and iron deficiency prevalence comparable to the general population.
- Routine monitoring for anemia and iron deficiency is recommended for children with Down syndrome.
- Prompt intervention can mitigate potential negative impacts on development.
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