[Activity of proteolytic enzymes and their inhibitors in large intestine tumors]

Activity of proteolytic enzymes and their inhibitors was studied in malignant and benign tumors of large intestine from 133 patients. Activity of proteinases was distinctly higher in malignant tumors as compared with unaltered tissue, while in benign tumor the enzymatic activity was similar to that of unaltered tissue. Inhibitor of proteinases exhibited lower activity in malignant tumor as compared with unaltered tissue and benign tumor. After irradiation treatment of tumors activity of the proteinases inhibitor was practically unaltered, while the enzymatic activity was distinctly decreased.