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Updated: May 29, 2026
07:04
Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
[Allergy to materials used in dental procedures]
Martha Patricia Valencia Zavala1, Manuel Anastacio Sánchez Olivas, Guillermo Velázquez Sámano
1Servicio de Alergia e Inmunología Clínica, Hospital General de México, México, DF, Mexico. valenciazavala@hotmail.com.
Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|September 28, 2011
Summary
Dental biomaterials can cause adverse pathological effects, including allergic reactions and cellular dysfunction, in susceptible patients. Increased awareness and research are crucial for timely diagnosis and effective patient care.
Area of Science:
- Biomaterials Science
- Dental Medicine
- Toxicology
Background:
- Dental biomaterials are integral to modern clinical dentistry.
- Potential adverse effects of these materials on oral tissues and systemic health are a growing concern.
Purpose of the Study:
- To review the existing literature on the pathological effects of materials used in clinical dentistry.
- To highlight the increasing incidence and underdiagnosis of pathologies related to dental materials.
Main Methods:
- A comprehensive literature search was conducted using PubMed.
- Keywords included "dental biomaterial," "odontologic toxicity," "odontologic allergy," "dental allergens," and "dental resins."
- Articles were selected based on their direct relevance to the pathological effects of dental biomaterials.
Main Results:
- Dental biomaterials can induce significant biological alterations in sensitized individuals, affecting cellular functions like dentinogenesis and tissue repair.
- Observed effects include toxicity, mutagenicity, and the release of antigens/allergens, leading to diverse immune and allergic reactions (immediate and delayed).
- These reactions can manifest with varying severity and extent, potentially causing extraoral damage.
Conclusions:
- The incidence of pathologies arising from dental materials is increasing, often due to a lack of awareness and delayed diagnosis.
- Further research into the harmful effects and pathological manifestations of dental biomaterials is essential.
- Enhanced dissemination of knowledge to dental professionals, physicians, and allergists is needed for improved patient management.
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