Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 29, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles
10:13

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

Selective particle trapping using an oscillating microbubble.

Priscilla Rogers1, Adrian Neild

  • 1Department of Mechanical and Aerospace Engineering, Monash University, Clayton, VIC 3800, Australia.

Lab on a Chip
|September 28, 2011
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microfluidic-assisted self-assembly of information-bearing oligomers.

Nanoscale·2026
Same author

Refined trajectory smoothing and deep learning classification of human sperm motility.

Human reproduction (Oxford, England)·2026
Same author

An Artificial Intelligence-Based Computer Vision Model for Human Sperm Concentration, Motility, and Kinematics Analysis.

Smart medicine·2026
Same author

Open Microfluidic Cell Culture in Hydrogels Enabled by 3D-Printed Molds.

Bioengineering (Basel, Switzerland)·2025
Same author

Repeated pulses of ultrasound maintain sperm motility.

Lab on a chip·2024
Same author

Accurate Low Complexity Quadrature Angular Diversity Aperture Receiver for Visible Light Positioning.

Sensors (Basel, Switzerland)·2024
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026
Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026
Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026
See all related articles

Acoustically-excited oscillating bubbles can selectively trap and sort particles in microfluidic lab-on-a-chip devices. This method utilizes bubble size to control forces, enabling size- and density-based particle manipulation.

Area of Science:

  • Microfluidics and Lab-on-a-Chip (LOC) Technology
  • Acoustic Manipulation and Particle Sorting
  • Biotechnology and Analytical Chemistry

Background:

  • Effective isolation and sorting of analytes are critical for the functionality of lab-on-a-chip devices.
  • Existing microfluidic techniques face challenges in achieving selective particle manipulation within complex volumes.
  • Acoustic forces offer a promising non-contact method for controlling microscale objects.

Purpose of the Study:

  • To investigate the use of acoustically-excited oscillating bubbles for selective particle trapping in microfluidic systems.
  • To demonstrate particle sorting based on both size and density using oscillating bubbles.
  • To analyze the interplay of microstreaming drag and secondary Bjerknes forces for particle manipulation.

Main Methods:

More Related Videos

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
08:19

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System

Published on: May 9, 2021

Optical Trapping of Nanoparticles
13:39

Optical Trapping of Nanoparticles

Published on: January 15, 2013

Related Experiment Videos

Last Updated: May 29, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles
10:13

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
08:19

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System

Published on: May 9, 2021

Optical Trapping of Nanoparticles
13:39

Optical Trapping of Nanoparticles

Published on: January 15, 2013

  • Utilized acoustically-excited oscillating bubbles within microfluidic channels.
  • Investigated the influence of bubble size and resonant frequency on particle interaction.
  • Performed theoretical analysis to model the forces (microstreaming drag and secondary Bjerknes force) acting on particles.

Main Results:

  • Achieved selective particle trapping, with selectivity dependent on particle size and density.
  • Demonstrated that bubble size dictates whether drag or secondary Bjerknes force dominates, controlling attraction or repulsion.
  • Confirmed theoretical predictions with experimental findings, showing good agreement.
  • Showcased density-based trapping, where denser particles are preferentially attracted due to a stronger secondary Bjerknes force.

Conclusions:

  • Oscillating bubbles provide a versatile and effective mechanism for particle trapping and sorting in microfluidic devices.
  • The presented method offers precise control over particle manipulation by tuning bubble acoustics.
  • This technique holds significant potential for advancing lab-on-a-chip applications requiring analyte separation.