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Updated: May 29, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
Published on: April 7, 2020
Development and validation of a nighttime sleep diary in asthmatic children
Shigemi Yoshihara1, Noriko Kanno, Hironobu Fukuda
1Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan. shigemi@dokkyomed.ac.jp
Insights
A new nighttime sleep diary effectively monitors asthma control in young children. This validated tool simplifies tracking symptoms like nighttime awakenings and coughs, aiding clinical management.
Area of Science:
- Pediatrics
- Respiratory Medicine
- Clinical Trial Methodology
Background:
- Asthma management in infants and young children requires reliable monitoring tools.
- Traditional asthma diaries can be lengthy and burdensome for parents and children.
- Assessing clinical control necessitates tracking both nighttime and daytime symptoms.
Purpose of the Study:
- To develop and validate a concise "nighttime sleep diary" for pediatric asthma.
- To evaluate the practicality and validity of the shortened diary for monitoring asthma control.
- To establish the correlation between nighttime awakenings and overall asthma symptom severity.
Main Methods:
- A prospective 6-week study involving 40 children (6 months to 6 years) with asthma.
- Participants were treated with nebulized budesonide or cromolyn sodium.
- The "nighttime sleep diary" focused on nighttime awakenings and was validated against traditional diary metrics.
Main Results:
- The nighttime sleep diary demonstrated validity and practicality for monitoring pediatric asthma.
- Nighttime awakening scores positively correlated with nighttime and daytime asthma symptom scores.
- A significant association was found between nighttime awakenings and the number of coughing days.
Conclusions:
- The "nighttime sleep diary" is a simple, useful instrument for tracking daily asthma symptom fluctuations in young children.
- This shortened diary aids in monitoring clinical control of asthma in pediatric populations.
- The findings support the use of the nighttime sleep diary in routine pediatric asthma care.
Abstract:
The aim of this study was to derive a shorter version of the asthma diary, 'a nighttime sleep diary' from the traditional asthma diary (original version). The nighttime sleep diary mainly consisted of nighttime awakening that met the criteria of validity and practicality necessary for monitoring clinical control in infants and young children with asthma symptoms. Validation of the diary was performed in a 6-week prospective study of 40 children aged 6 months to 6 years treated with nebulized budesonide inhalation suspension or cromolyn sodium nebulized solution. The nighttime awakening score was significantly and positively associated with the nighttime asthma symptom score and daytime asthma symptom score along with the number of days with a cough. Therefore, the nighttime sleep diary is a simple and useful instrument to monitor day-to-day fluctuations in young children with asthma.
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