Related Experiment Video
Updated: May 29, 2026

In Vitro Method to Study Sex-Based Differences in Conjunctival Goblet Cells
Published on: July 28, 2023
Does the probability of developing ocular trauma-related visual deficiency differ between genders?
Dulce Milagros Razo Blanco-Hernández1, Jessica Daniela Valencia-Aguirre, Virgilio Lima-Gómez
1División de Investigación, Hospital Juárez de México, Secretaría de Salud, México, D.F., Mexico.
Background:
Ocular trauma affects males more often than females, but the impact of this condition regarding visual prognosis is unknown. We undertook this study to compare the probability of developing ocular trauma-related visual deficiency between genders, as estimated by the ocular trauma score (OTS).
Methods:
We designed an observational, retrospective, comparative, cross-sectional and open-label study. Female patients aged ≥6 years with ocular trauma were included and matched by age and ocular wall status with male patients at a 1:2 male/female ratio. Initial trauma features and the probability of developing visual deficiency (best corrected visual acuity <20/40) 6 months after the injury, as estimated by the OTS, were compared between genders. The proportion and 95% confidence intervals (95% CI) of visual deficiency 6 months after the injury were estimated. Ocular trauma features and the probability of developing visual deficiency were compared between genders (χ(2) and Fisher's exact test); p value <0.05 was considered significant.
Results:
Included were 399 eyes (133 from females and 266 from males). Mean age of patients was 25.7 ± 14.6 years. Statistical differences existed in the proportion of zone III in closed globe trauma (p = 0.01) and types A (p = 0.04) and type B (p = 0.02) in open globe trauma. The distribution of the OTS categories was similar for both genders (category 5: p = 0.9); the probability of developing visual deficiency was 32.6% (95% CI = 24.6 to 40.5) in females and 33.2% (95% CI = 27.6 to 38.9) in males (p = 0.9).
Conclusions:
The probability of developing ocular trauma-related visual deficiency was similar for both genders. The same standard is required.
Related Concept Videos
Photoreceptors and Visual Pathways
Accessory Structures of the Eye
X-linked Traits
