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Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
Published on: March 16, 2017
A copper(II) rhodamine complex with a tripodal ligand as a highly selective fluorescence imaging agent for nitric
Xiaoyue Hu1, Jian Wang, Xiang Zhu
1State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, 116024, China.
Chemical Communications (Cambridge, England)
|September 29, 2011
Abstract:
A copper(II) complex CuRBT with a ring-closed rhodamine-containing tripodal ligand was synthesized as a highly selective fluorescent imaging agent for nitric oxide (NO). It featured a 700-fold fluorescent enhancement toward NO from a dark-background with the detection limit of NO about 1 nM in aqueous solution and could be applied for monitoring intracellular NO.
