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Fluorescence properties of glafenine
Journal of Pharmaceutical Sciences
|December 1, 1977
Summary
Glafenine
Area of Science:
- Analytical Chemistry
- Photochemistry
- Organic Chemistry
Background:
- Glafenine exhibits fluorescence, a property influenced by its molecular structure.
- Understanding these fluorescence properties is crucial for analytical applications.
Purpose of the Study:
- To investigate the fluorescence characteristics of glafenine.
- To establish correlations between glafenine's fluorescence and UV absorbance.
- To explore its utility in analytical determinations across various solvents.
Main Methods:
- Spectroscopic analysis of glafenine.
- UV-Visible absorption and fluorescence emission measurements.
- Determination of linearity, detection limits, and Stokes shifts in different solvents.
Main Results:
- The anthranilic acid moiety significantly contributes to glafenine's fluorescence.
- A direct correlation was observed between fluorescence capacity and UV absorbance.
- Linear relationships between emission intensity and concentration were established.
- Limiting detectable concentrations and Stokes shifts were quantified in ether, benzene, and ethanol.
Conclusions:
- Glafenine's fluorescence is linked to its anthranilic acid core.
- The study validates glafenine as a fluorescent compound for analytical purposes.
- Quantitative analytical methods for glafenine can be developed based on its fluorescence and UV absorbance properties.