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[Studies on the chemical constituents from Conyza canadensis]
Hong-Li Liu1, Bai-Lian Liu, Guo-Cai Wang
1Institute of Traditional Chinese Medicine & Natural Products/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, China.
Objective:
To study the chemical constituents of Conyza canadensis.
Methods:
Chromatographic methods including HP20 macroporous resin, silica gel, Sephadex LH-20 and eighteen alkyl silane bonding silica gel (ODS) were used for the isolation and purification of Conyza canadensis. The structures of the obtained compounds were identified by physical chemistry and spectroscopic data.
Results:
Six compounds were isolated from ethanol-extraction of water area of C. canadensis and identified as Eugenyl beta-Psd (1), scutellarin (2), luteolin-7-O-beta-D-glucuronide (3), quercetin (4), quercetin-3-O-beta-D-glucopyranoside (5) and luteolin (6).
Conclusion:
Compounds 1,3,5 and 6 are isolated from C. canadensis for the first time.
