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Related Experiment Video

Updated: May 29, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Pemphigus vulgaris.

Sandhya Tamgadge¹, Avinash Tamgadge, Daivat M Bhatt

¹Department of Oral and Maxillofacial Pathology and Microbiology, Padmashree Dr. D.Y. Patil Dental College and Hospital, Navi Mumbai, India.

Contemporary Clinical Dentistry

|September 30, 2011

Summary

This summary is machine-generated.

Pemphigus vulgaris is an autoimmune disease causing oral lesions that can spread. Early diagnosis by dental professionals is crucial for better patient outcomes.

Keywords:

Autoimmune disease bullae mucous membrane pemphigus vulgaris

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Granulocyte-dependent Autoantibody-induced Skin Blistering

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Published on: October 12, 2012

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Published on: June 17, 2025

Area of Science:

Autoimmune diseases
Dermatology
Oral medicine

Background:

Pemphigus vulgaris is a chronic autoimmune mucocutaneous disease.
It initially presents as intraoral lesions before affecting mucous membranes and skin.
The exact etiology remains unknown, despite significant research interest.

Observation:

The disease involves autoantibodies targeting intercellular substances.
Patients are frequently misdiagnosed, leading to delayed treatment.
Dental professionals play a key role in identifying early signs.

Findings:

Pemphigus vulgaris is characterized by autoantibody production.
Delayed diagnosis impacts the disease's prognosis and progression.
Familiarity with clinical manifestations aids early detection.

Implications:

Early diagnosis and treatment by dental professionals improve patient prognosis.
Increased awareness can reduce misdiagnosis and improper treatment durations.
Understanding pemphigus vulgaris is vital for effective patient management.