Malignant Non-Odontogenic Tumors of the Oral Cavity - Single Institutional Retrospective Study of Three Decades

Malignant non-odontogenic tumors of the oral cavity remain understudied in India, despite their global prevalence. This retrospective analysis examined cases from a single institution in Maharashtra between 1990 and 2021, focusing on patient demographics, clinical presentations, and histopathological features. Oral squamous cell carcinoma (OSCC) emerged as the predominant malignancy, with epithelial malignancies accounting for 98.6% of cases. A slight male predominance was observed. Buccal mucosa was the most frequent site of occurrence, with tobacco chewing identified as the primary risk factor. This study underscores the need for increased attention to oral malignancies in routine medical examinations and calls for more comprehensive statistical analysis to inform clinical practice and public health strategies.