[Therapeutic strategy and prognosis of malignant struma]

The systematic application of combined treatment modalities including surgery, radiotherapy and suppressive hormone administration is based on a biologically relevant histomorphologic tumour classification. Although the principle of an aggressive therapeutic approach is still valid meantime a limited radicality has proven equally successful for selected early cases. On the other hand an even extended radical strategy is followed by repeated surgery for local recurrencies and metastatic lesions.