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Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

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Related Experiment Video

Updated: May 28, 2026

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
06:40

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies

Published on: January 11, 2019

Diffusion tensor imaging in carpal tunnel syndrome.

Neslihan Taşdelen1, Bengi Gürses, Özgür Kiliçkesmez

  • 1Department of Radiology, Yeditepe University School of Medicine, İstanbul, Turkey. ntasdelen@yeditepe.edu.tr

Diagnostic and Interventional Radiology (Ankara, Turkey)
|October 1, 2011
PubMed
Summary

Diffusion tensor imaging shows promise for diagnosing carpal tunnel syndrome. Fractional anisotropy measurements of the median nerve can help identify the condition with high sensitivity and specificity.

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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

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Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
06:40

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies

Published on: January 11, 2019

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
07:00

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

Area of Science:

  • Neuroimaging
  • Radiology
  • Medical Diagnostics

Background:

  • Carpal tunnel syndrome (CTS) is a common condition causing median nerve compression.
  • Accurate diagnosis is crucial for effective treatment and preventing nerve damage.
  • Current diagnostic methods may have limitations in sensitivity and specificity.

Purpose of the Study:

  • To evaluate the effectiveness of diffusion tensor imaging (DTI) in diagnosing CTS.
  • To identify quantitative imaging parameters from DTI that aid in CTS diagnosis.

Main Methods:

  • Prospective evaluation of median nerves in CTS patients and healthy controls using 3T MRI.
  • Diffusion tensor imaging (DTI) and T1-weighted sequences were acquired.
  • Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured at the carpal tunnel and along the whole median nerve.

Main Results:

  • Significantly lower FA values were observed in CTS patients compared to controls (P < 0.001).
  • ADC measurements did not show significant differences between groups.
  • Receiver operator characteristic analysis yielded cut-off FA values of 0.554 (focal) and 0.660 (whole nerve) with high sensitivity and specificity.

Conclusions:

  • Diffusion tensor imaging, specifically fractional anisotropy measurements, shows potential as a diagnostic tool for carpal tunnel syndrome.
  • DTI-derived FA may offer a quantitative biomarker for CTS diagnosis.