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Related Experiment Videos

Prophylactic digitalization for thoracotomy: a reassessment.

A J Ritchie1, P Bowe, J R Gibbons

  • 1Department of Cardiothoracic Surgery, Royal Victoria Hospital, Belfast, Northern Ireland.

The Annals of Thoracic Surgery
|July 1, 1990
PubMed
Summary
This summary is machine-generated.

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Prophylactic digoxin did not significantly reduce cardiac arrhythmia incidence in elective thoracic surgery patients. This study suggests reconsidering the routine use of digoxin before these operations.

Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Clinical Pharmacology

Background:

  • Cardiac arrhythmias are a common complication following thoracic surgery.
  • Digoxin is sometimes used prophylactically to prevent arrhythmias in this patient population.

Purpose of the Study:

  • To evaluate the efficacy of prophylactic digoxin in preventing cardiac arrhythmias in patients undergoing elective thoracic operations.

Main Methods:

  • A prospective, controlled, randomized clinical study.
  • 140 patients undergoing elective thoracic operations were included.
  • Patients were divided into two groups: one received digoxin, the other did not.

Main Results:

  • The overall mortality rate was 5.7%.

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  • No significant difference in the incidence of cardiac arrhythmia was observed between the digoxin group and the control group.

    • Conclusions:

    • The prophylactic use of digoxin in elective thoracic operations may not be effective in preventing cardiac arrhythmias.
    • Clinical practice guidelines regarding digoxin use in this setting should be revised.