[Perioperative antibiotic prophylaxis in surgery]

Surgical site infections - SSI belong to one of the most frequent and serious post-operative complications occurring in patients. They lead to extended hospitalization period, to increase of treatment costs, morbidity and mortality among patients. The surgical antibiotic prophylaxis is one of the most significant procedures which goal is to reduce infectious complications and to complement surgical effects. Proper surgical antibiotic prophylaxis should be distinguished by: appropriate time of application and administration adequate to the kind of treatment and quality of the drug, proper selection of the antibiotic which considers microbiological as well as pharmacological conditions which has established clinical effectiveness.