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Updated: May 28, 2026

Assessing Specificity of Anticancer Drugs In Vitro
Published on: March 23, 2016
Analysis of anticancer drugs: a review
Susanne Nussbaumer1, Pascal Bonnabry, Jean-Luc Veuthey
1Pharmacy, Geneva University Hospitals (HUG), Geneva, Switzerland.
Abstract:
In the last decades, the number of patients receiving chemotherapy has considerably increased. Given the toxicity of cytotoxic agents to humans (not only for patients but also for healthcare professionals), the development of reliable analytical methods to analyse these compounds became necessary. From the discovery of new substances to patient administration, all pharmaceutical fields are concerned with the analysis of cytotoxic drugs. In this review, the use of methods to analyse cytotoxic agents in various matrices, such as pharmaceutical formulations and biological and environmental samples, is discussed. Thus, an overview of reported analytical methods for the determination of the most commonly used anticancer drugs is given.
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