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Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Updated: May 28, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
12:03

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Published on: December 9, 2016

Primary renal Ewing's sarcoma.

Adrián Husillos Alonso1, Mercedes Moralejo Gárate, Felipe Herranz Amo

  • 1Urology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain. adrhusillos@hotmail.com

Archivos Espanoles De Urologia
|October 4, 2011
PubMed
Summary
This summary is machine-generated.

Ewing's sarcoma of the kidney is a rare cancer in young adults. Successful treatment involves surgery and chemotherapy, leading to remission in these reported cases.

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Last Updated: May 28, 2026

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Area of Science:

  • Oncology
  • Nephrology
  • Pathology

Background:

  • Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) is rare in the kidney.
  • It primarily affects young adults and has a poor prognosis.

Observation:

  • Two cases of primary renal ES/PNET in men are presented.
  • One case involved a tumor thrombus extending into the vena cava.

Findings:

  • Both patients underwent nephrectomy and adjuvant chemotherapy.
  • Both patients achieved complete remission and remain disease-free.

Implications:

  • Multimodal treatment combining surgery and chemotherapy is effective for renal ES/PNET.
  • Early diagnosis and aggressive treatment are crucial for improving outcomes in this rare malignancy.