Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...

The Skin Microbiota

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

Overview of Regeneration and Repair

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...

Inflammatory Response

Inflammatory Response

An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...

Confocal Fluorescence Microscopy

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Azithromycin-Induced Linear Fixed Drug Eruption: A Rare Instance.

Indian dermatology online journal·2021

Same author

Lichen Planus Pigmentosus: The Controversial Consensus.

Indian journal of dermatology·2016

Same author

Topical Steroid Damaged/Dependent Face (TSDF): An Entity of Cutaneous Pharmacodependence.

Indian journal of dermatology·2016

Same author

Serendipity and its role in dermatology.

Indian journal of dermatology·2015

Same author

Side-effects of topical steroids: A long overdue revisit.

Indian dermatology online journal·2014

Same author

Topical corticosteroid misuse: the Indian scenario.

Indian journal of dermatology·2014

Search research articles

Related Experiment Video

Updated: May 28, 2026

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Published on: April 20, 2016

Cytokines in dermatology - a basic overview.

Arijit Coondoo¹

¹Department of Dermatology, KPC Medical College, Kolkata, West Bengal, India.

Indian Journal of Dermatology

|October 4, 2011

Summary

This summary is machine-generated.

Cytokines are crucial signaling proteins regulating immunity and inflammation. While vital for cellular communication, persistent release can lead to chronic diseases.

Keywords:

Cutaneous tissues cytokines signaling molecules

More Related Videos

Generation and Culturing of Primary Human Keratinocytes from Adult Skin

Generation and Culturing of Primary Human Keratinocytes from Adult Skin

Published on: December 22, 2017

Related Experiment Videos

Last Updated: May 28, 2026

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Published on: April 20, 2016

Generation and Culturing of Primary Human Keratinocytes from Adult Skin

Generation and Culturing of Primary Human Keratinocytes from Adult Skin

Published on: December 22, 2017

Area of Science:

Biochemistry
Immunology
Cell Biology

Background:

Cytokines are proteins and glycoproteins produced by various cells upon immune stimulation.
They act as signaling molecules, transmitting signals through specific cell surface receptors.
Cytokines are transiently released emergency molecules essential for cellular communication.

Purpose of the Study:

To elucidate the multifaceted roles of cytokines in biological processes.
To understand the implications of cytokine dysregulation in disease pathogenesis.

Main Methods:

Review of scientific literature on cytokine signaling pathways.
Analysis of cytokine involvement in immune responses and cellular functions.

Main Results:

Cytokines regulate key cellular processes including immunity, inflammation, proliferation, and apoptosis.
Persistent cytokine release is implicated in the development of chronic diseases.

Conclusions:

Cytokines are critical mediators of cellular communication and immune regulation.
Understanding cytokine dynamics is essential for addressing inflammatory and chronic conditions.