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A clinical study of 125 patients with phrynoderma
S Ragunatha1, V Jagannath Kumar, S B Murugesh
1Department of Dermatology, Venereology and Leprosy, Shri B.M. Patil Medical College, Hospital and Research Centre, BLDE University, Bijapur .
Indian Journal of Dermatology
|October 4, 2011
Summary
Phrynoderma, a follicular hyperkeratosis, presents with characteristic skin lesions, often linked to nutritional deficiencies. This study highlights its clinical features and association with vitamin A and B-complex deficiencies.
Area of Science:
- Dermatology
- Nutritional Science
- Clinical Research
Background:
- Phrynoderma is a form of follicular hyperkeratosis.
- Its etiology is often linked to various nutritional deficiencies.
Purpose of the Study:
- To define the clinical characteristics of phrynoderma.
- To investigate its association with signs of nutritional deficiencies.
Main Methods:
- A descriptive, cross-sectional study involved 125 patients with phrynoderma.
- Data collected included patient history, lesion morphology, distribution, and signs of nutritional deficiencies.
Main Results:
- Phrynoderma constituted 0.51% of dermatology outpatient visits.
- Lesions were typically asymptomatic, bilateral, symmetrical, and localized to elbows and knees.
- Signs of vitamin A and B-complex deficiencies were observed in 3.2% and 9.6% of patients, respectively.
Conclusions:
- Phrynoderma exhibits distinct clinical features.
- It is likely a multifactorial condition influenced by nutritional status, local factors, and environmental influences.
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