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Necrolytic acral erythema in an adolescent
Kelly Ridder1, Cassey Vessels1, Kristy Kennedy1
1Division of Dermatology, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.
Pediatric Dermatology
|October 5, 2011
Summary
Necrolytic acral erythema (NAE) is a distinct skin condition often linked to hepatitis C virus infection. This summary reviews NAE
Area of Science:
- Dermatology
- Hepatology
- Pathology
Background:
- Necrolytic acral erythema (NAE) was first described in 1996 as a distinct entity within the necrolytic erythema family.
- NAE is now recognized as a cutaneous manifestation of hepatitis C virus (HCV) infection, serving as a marker for systemic disease.
Observation:
- NAE presents with burning, pruritic papules and vesiculation on the feet, evolving into hyperkeratotic plaques with specific erythema and scaling.
- Clinical and histopathologic features distinguish NAE from conditions like psoriasis or inflammatory dermatitis.
Findings:
- The study reports a case of NAE in a 17-year-old patient.
- A literature review further solidifies NAE's characteristics and association with HCV.
Implications:
- Accurate diagnosis of NAE is crucial for identifying underlying systemic conditions like HCV.
- Understanding NAE contributes to the broader knowledge of necrolytic erythema and its clinical significance.
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