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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

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Polymers for colon targeted drug delivery.

H Rajpurohit¹, P Sharma, S Sharma

¹Faculty of Pharmaceutical Sciences, Jodhpur National University, Jodhpur - 342 008, India.

Indian Journal of Pharmaceutical Sciences

|October 5, 2011

Summary

Oral colon targeted drug delivery systems protect medications from degradation in the upper gastrointestinal tract. These systems ensure precise drug release in the colon for effective local or systemic pharmacotherapy.

Keywords:

Biodegradable polymers colon targeted delivery controlled delivery polysaccharides

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Area of Science:

Pharmacotherapy
Drug Delivery Systems
Polymer Science

Background:

Colon targeted drug delivery is crucial for effective pharmacotherapy, enabling local and systemic drug administration.
Oral colon targeted systems protect drugs from degradation in the stomach and small intestine.
These systems are designed for abrupt or controlled drug release specifically in the proximal colon.

Purpose of the Study:

To review various polymer types suitable for formulating colon targeted drug delivery systems.
To highlight the importance of colon targeting in modern drug delivery strategies.

Main Methods:

Literature review of existing colon targeted drug delivery systems.
Analysis of polymer properties relevant to colon targeting and drug release.

Main Results:

Multiple drug delivery systems have been developed for quantitative colon delivery and triggered drug release.
A variety of polymers can be employed in the formulation of these specialized systems.

Conclusions:

Colon targeted drug delivery offers significant advantages for therapeutic agent administration.
The selection of appropriate polymers is key to successful colon targeted drug delivery system design.