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Updated: May 28, 2026

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
Published on: July 26, 2019
[Bioinformatics technologies for the analysis of antigenic evolution of influenza viruses]
1Department of Bioinformatics, Hokkaido University Research Center for Zoonosis Control PRESTO, Japan Science and Technology Agency. itok@czc.hokudai.ac.jp
Abstract:
Human influenza viruses mutate from time to time, causing annual epidemics worldwide. The strong immune pressure in the human population selects a new variant every year, and the antigenic change is one of the primary reasons why vaccination is not a perfect measure to control seasonal influenza. Thus prediction of antigenic change of influenza A virus has been one of the major public health goals. In this review bioinformatics technologies that have been developed to achieve this goal were summarized.
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