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Comparative Analysis of Automatic Fecal Analyzer versus Direct Wet Smear Microscopy for Detecting Parasitic Infections in Stool Samples
Published on: April 25, 2025
[Retrospective analysis of 39 child cases of paragonimiasis]
Mei Guo1, Wei Wang, Jian-yu Jiang
1Pediatric Intensive Care Unit, Chongqing Three Gorges Central Hospital, Chongqing 400010, China. guomeiguofeng@163.com
Insights
Paragonimiasis in children often presents as polyserositis or cerebral disease. Praziquantel treatment, with or without surgery, showed high efficacy in treating pediatric paragonimiasis.
Area of Science:
- Medical Parasitology
- Pediatric Infectious Diseases
- Clinical Medicine
Context:
- Retrospective analysis of 39 children diagnosed with paragonimiasis.
- Treatment data collected from Chongqing Three Gorges Central Hospital (2008-2010).
- Focus on pediatric cases aged 3-10 years.
Purpose:
- To analyze clinical characteristics and treatment outcomes of pediatric paragonimiasis.
- To evaluate the effectiveness of praziquantel and surgical interventions.
- To understand the prevalence of polyserositis and cerebral paragonimiasis in children.
Summary:
- Polyserositis (64.1%) and cerebral paragonimiasis (35.9%) were the main clinical types observed.
- Respiratory distress was common in polyserositis, while neurological symptoms like headache and vomiting dominated cerebral cases.
- Treatment with praziquantel alone or combined with surgery resulted in a 97.4% cure or improvement rate.
Impact:
- Highlights the significant clinical manifestations of paragonimiasis in children.
- Demonstrates the effectiveness of praziquantel-based treatment regimens.
- Provides valuable data for the management of pediatric parasitic infections.
Abstract:
Clinical data of 39 children with paragonimiasis treated in Chongqing Three Gorges Central Hospital during 2008-2010 were retrospectively analyzed. The cases aged from 3 to 10 years old, with 25 cases of polyserositis (64.1%), 14 cases of cerebral paragonimiasis (35.9%). Among the cases of polyserositis, all showed dyspnea,tachypnea and diminished respiration (100%). Other symptoms or signs included purulent pleurisy, orthopnea, restricted activity, distant heart sounds, purulent pericarditis, abdominal distension, and hepatomegaly. In the 14 cases of cerebral paragonimiasis, 10 cases (71.4%) complained headache, 8 cases (57.1%) with vomiting, and other symptoms such as seizures, limb rigidity associated with conscious disturbance. Eight patients were treated with surgery and praziquantel, while others with praziquantel alone. After treatment 25 cases (64.1%) were cured, 13 cases (33.3%) improved, and 1 case (2.6%) showed no change.
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