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Updated: May 28, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Universal acquired melanosis in siblings
Snehansu Chakraborti1, Tarak Nath Ghosh, Shankha Subhra Nag
1Department of Pediatrics, Burdwan Medical College and Hospital, Burdwan, West Bengal, India. drsnehansu.bmch11@gmail.com
Abstract:
Generalized pigmentation in a child may be seen in a variety of disorders which can be clinically differentiated. Accuracy of diagnosis can be increased by classifications based on both clinical and histological findings. The authors report a case of siblings in whom hyperpigmentation started at age of about 6 mo and was progressing. Histology of skin revealed shortening and blunting of rete ridges with presence of melanocytes in stratum basal layer. This is a rare type of hypermelanosis and termed as universal acquired melanosis or carbon baby syndrome. This is a rare presentation and first case report in siblings.
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