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Updated: May 28, 2026

11:19
Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
Published on: July 4, 2016
Electron spin labeling reveals the highly dynamic N-terminal arms of the SOS mutagenesis protein UmuD
Jaylene N Ollivierre1, David E Budil, Penny J Beuning
1Department of Chemistry & Chemical Biology, Northeastern University, Boston, USA.
Molecular Biosystems
|October 7, 2011
Abstract:
Electron paramagnetic resonance (EPR) spectroscopy was used to probe the conformational dynamics of the N-terminal arms of the umuD gene products. We determined that the arms of UmuD(2) display a large degree of motion, are largely unbound from the globular C-terminal domain, and that the free energy of dissociation is +2.1 kJ mol(-1).

