Related Experiment Video
Updated: May 28, 2026

04:04
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Central odontogenic fibroma: a case report.
1Department of Oral and Maxillofacial Radiology, School of Dentistry, Pusan National University, Busan, Korea.
Imaging Science in Dentistry
|October 7, 2011
Summary
A rare central odontogenic fibroma was found in a 17-year-old male. This case highlights the importance of considering this benign neoplasm in the differential diagnosis of mandibular radiolucencies.
Area of Science:
- Oral and Maxillofacial Pathology
- Odontogenic Neoplasms
- Tumor Biology
Background:
- Central odontogenic fibroma (COF) is an uncommon benign odontogenic neoplasm.
- It originates from the odontogenic ectomesenchyme, a key component in tooth development.
- Understanding COF is crucial for accurate diagnosis and treatment planning in dentistry.
Observation:
- A case report details a 17-year-old male with a central odontogenic fibroma.
- The lesion presented as a multilocular radiolucency in the right mandibular condyle region.
- The radiolucency had partially ill-defined borders, extending towards the mandibular third molar.
Findings:
- The radiographic appearance necessitated a broad differential diagnosis.
- Potential diagnoses ranged from benign lesions like ameloblastic fibroma and odontogenic myxoma.
- More aggressive entities such as desmoplastic fibroma, juvenile aggressive fibromatosis, and fibrosarcoma were also considered.
Implications:
- This case underscores the diagnostic challenges posed by central odontogenic fibroma.
- Accurate differentiation from other mandibular lesions is critical for appropriate patient management.
- Further research into the specific characteristics and behavior of COF is warranted.