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Updated: May 28, 2026

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain
Published on: May 7, 2018
Effects of pH on potassium: new explanations for old observations
Peter S Aronson1, Gerhard Giebisch
1Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520-8029, USA. peter.aronson@yale.edu
Abstract:
Maintenance of extracellular K(+) concentration within a narrow range is vital for numerous cell functions, particularly electrical excitability of heart and muscle. Potassium homeostasis during intermittent ingestion of K(+) involves rapid redistribution of K(+) into the intracellular space to minimize increases in extracellular K(+) concentration, and ultimate elimination of the K(+) load by renal excretion. Recent years have seen great progress in identifying the transporters and channels involved in renal and extrarenal K(+) homeostasis. Here we apply these advances in molecular physiology to understand how acid-base disturbances affect serum potassium.
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