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Related Experiment Video

Updated: May 28, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
07:05

Use of Human Perivascular Stem Cells for Bone Regeneration

Published on: May 25, 2012

Postextraction osteotome sinus floor elevation technique using plasma-rich growth factors.

Silvio Taschieri1, Massimo Del Fabbro

  • 1Dental Clinic, Department of Health Technologies, Università degli Studi di Milano, Milan, Italy.

Implant Dentistry
|October 12, 2011
PubMed
Summary

This study shows a modified osteotome sinus lift technique with immediate implants and platelet-derived fibrin is effective for restoring maxillary premolars. Patients experienced high satisfaction with no implant failures over 35 months.

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Area of Science:

  • Dental Implantology
  • Periodontology
  • Regenerative Dentistry

Background:

  • Maxillary premolar sites often require bone augmentation for successful dental implant placement.
  • Traditional sinus lift procedures can be invasive and may require separate grafting stages.

Purpose of the Study:

  • To evaluate a modified osteotome sinus floor elevation technique combined with immediate postextraction implant placement.
  • To assess the efficacy of using a platelet-derived fibrin plug as an adjunct in this procedure.

Main Methods:

  • Fifteen patients with nonrestorable maxillary premolars underwent extraction, osteotome sinus elevation with a fibrin clot, and immediate implant placement.
  • Implants were embedded with plasma rich in growth factors (PRGF).

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Last Updated: May 28, 2026

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Main Results:

  • No implant failures occurred during a mean follow-up of 35 months.
  • Average membrane lift was 2.9 mm, with minimal marginal bone loss (0.36 mm) after 1 year.
  • Patients reported high satisfaction with function and aesthetics, with no adverse postoperative symptoms.

Conclusions:

  • The modified osteotome sinus floor elevation with immediate implants and PRGF is a viable and effective option.
  • This technique offers a predictable solution for rehabilitating fresh maxillary premolar extraction sockets.