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Plasmodesmata02:32

Plasmodesmata

The organs in a multicellular organism’s body are made up of tissues formed by cells. To work together cohesively, cells must communicate. One way that cells communicate is through direct contact with other cells. The points of contact that connect adjacent cells are called intercellular junctions.
Plasmodesmata01:20

Plasmodesmata

In a multicellular organism, cells must communicate to work together in a coordinated manner. One way that cells communicate is through direct contact with other cells. The points of contact that connect adjacent cells are called intercellular junctions.
Intercellular junctions are a feature of fungal, plant, and animal cells. However, different types of junctions are found in different kinds of cells. Intercellular junctions found in animal cells include tight junctions, gap junctions, and...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

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Related Experiment Video

Updated: May 28, 2026

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
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Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

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Sellar plasmacytomas: a concise review.

Rene Joukhadar1, Ken Chiu

  • 1Department of Diabetes, Endocrinology, and Metabolism, City of Hope National Medical Center, Duarte, CA 91010, USA. rjoukhadar@coh.org

Pituitary
|October 12, 2011
PubMed
Summary

Sellar plasmacytoma is frequently misdiagnosed as a pituitary adenoma. Early diagnosis improves management and avoids unnecessary surgery for this radiosensitive tumor.

Area of Science:

  • Neuro-oncology
  • Endocrinology
  • Pathology

Background:

  • Sellar plasmacytomas are rare tumors often misdiagnosed as non-functioning pituitary adenomas.
  • This diagnostic challenge can lead to delayed or incorrect treatment.

Purpose of the Study:

  • To review the literature on sellar plasmacytomas.
  • To identify key clinical, laboratory, radiological, and pathological features.
  • To provide insights into preoperative diagnosis and management.

Main Methods:

  • Literature review of reported sellar plasmacytoma cases.
  • Analysis of clinical presentation, laboratory findings, imaging, and pathology.
  • Detailed description of a new case.

Main Results:

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  • Sellar plasmacytomas present unique characteristics often overlooked.
  • Preoperative diagnosis is crucial for appropriate management.
  • These tumors are sensitive to radiation therapy.

Conclusions:

  • Improved awareness and diagnostic criteria are needed for sellar plasmacytoma.
  • Accurate preoperative diagnosis can guide treatment and improve patient outcomes.
  • Sellar plasmacytoma requires a distinct management strategy compared to pituitary adenomas.