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Related Experiment Video

Updated: May 28, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Majocchi's granuloma.

Aline Lopes Bressan¹, Roberto Souto da Silva, João Carlos Macedo Fonseca

¹Hospital Universitário Pedro Ernesto, Rio de Janeiro, Brasil. alinebressan@ig.com.br

Anais Brasileiros De Dermatologia

|October 12, 2011

Summary

This summary is machine-generated.

A 45-year-old man with prolonged superficial fungal skin infection (dermatophytosis) developed deep granuloma Majocchi due to incorrect antibiotic and corticosteroid treatment. Oral terbinafine effectively resolved the deep fungal infection.

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Last Updated: May 28, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Area of Science:

Dermatology
Mycology
Infectious Diseases

Background:

Superficial dermatophytosis can be misdiagnosed and treated inappropriately.
Prolonged use of antibiotics and corticosteroids may alter the course of fungal infections.

Observation:

A 45-year-old male presented with a long-standing superficial fungal skin infection.
The condition had progressed to a deep form, identified as granuloma Majocchi.
Inadvertent treatment with antibiotics and corticosteroids preceded the progression.

Findings:

Granuloma Majocchi represents a deep form of dermatophytosis.
The patient's condition responded successfully to oral terbinafine therapy.

Implications:

Accurate diagnosis and appropriate antifungal treatment are crucial for managing dermatophytosis.
Understanding the potential complications of incorrect treatment for fungal infections is important for clinicians.
Terbinafine is an effective oral antifungal agent for treating deep fungal infections like granuloma Majocchi.