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Updated: May 28, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
Diffuse alveolar hemorrhage: a rare manifestation of trauma
Patrick F Allan1, Darius K Amjadi, Ralph L Haynes
1Department of Pulmonary, Critical Care, and Sleep Medicine Landstuhl Regional Medical Center, CMR 402, Box 307, APO AE 09180, Landstuhl, Germany.
Objective:
Fat emboli syndrome (FES) is a disorder associated with both acute lung injury and acute respiratory distress syndrome. Both FES and diffuse alveolar hemorrhage (DAH) are bronchoscopically definable entities that may share a common etiology. We conducted a chart review analysis to examine the relationship between FES and DAH.
Methods:
Retrospective chart review.
Results:
Three cases of concurrent FES and DAH were identified. Long bone fracture and/or orthopedic procedures preceded all the events and were the likely inciting source for eventual acute lung injury. Bronchoalveolar lavage-evident DAH and FES was found in all these cases in association with hemoptysis and lung-attributed blood loss. Lung-protective ventilation and standard supportive care approaches proved sufficient in attaining good outcomes.
Conclusion:
Combined FES and DAH can occur in association with orthopedic injury and repair and are likely an under-recognized entity.
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