Related Experiment Video
Updated: May 28, 2026

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
Published on: August 13, 2015
Recurrent pain, stress, tender points and fibromyalgia in childhood: an exploratory descriptive clinical study
1Department of Paediatric, Karolinska University Hospital, Stockholm, Sweden. gosta.alfven@karolinska.se
Aims:
To study the occurrence of tender points associated with fibromyalgia and their relationship with the stress-related pattern of tender points in children with psychosomatic recurrent abdominal pain.
Methods:
In an exploratory descriptive study, 47 children aged 6-17 years with psychosomatic recurrent abdominal pain were examined for tender points associated with fibromyalgia and those associated with stress. The individual scores for these two types of tender point were correlated at inclusion and at follow-up after treatment.
Results:
At inclusion, all children had a score for stress tender points that was near the maximum. Eight satisfied the diagnostic criteria for fibromyalgia. The scores for stress and fibromyalgia tender points were correlated significantly at both inclusion (R = 0.42, p < 0.005) and follow-up (R = 0.74, p < 0.00005). At follow-up, the children who were free of pain had significantly lower scores for stress tender points (p < 0.001) and fibromyalgia tender points (p < 0.00001) than those who were not pain free.
Conclusions:
Children with psychosomatic pain can have an increased risk of developing fibromyalgia. A longer duration of pain and more locations in which pain is felt might increase this risk. In patients with a favourable outcome, the scores for stress tender points and fibromyalgia tender points decreased significantly.
Related Concept Videos
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Analgesia and Pain Management

