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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

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Related Experiment Video

Updated: May 28, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
03:50

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Published on: August 18, 2023

Chronic constipation in the elderly.

Juan F Gallegos-Orozco1, Amy E Foxx-Orenstein, Susan M Sterler

  • 1Division of Gastroenterology, Mayo Clinic in Arizona, Scottsdale, 85259, USA.

The American Journal of Gastroenterology
|October 13, 2011
PubMed
Summary

Constipation is a common gastrointestinal issue, particularly in older adults and women. This review covers its definition, diagnosis, and management, including new treatments for chronic constipation.

Related Experiment Videos

Last Updated: May 28, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
03:50

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Published on: August 18, 2023

Area of Science:

  • Gastroenterology
  • Geriatrics
  • Epidemiology

Background:

  • Constipation is a prevalent gastrointestinal disorder in Western societies.
  • Prevalence increases with age and is higher in females.
  • Chronic constipation significantly impacts quality of life and healthcare costs.

Purpose of the Study:

  • To review the definition, epidemiology, and diagnostic approach for chronic constipation in the elderly.
  • To discuss non-pharmacologic and pharmacologic management strategies for chronic constipation in older adults.
  • To provide an overview of emerging pharmacologic treatments for chronic constipation.

Main Methods:

  • Literature review focusing on chronic constipation in the elderly.
  • Synthesis of epidemiological data and diagnostic criteria.
  • Analysis of current and investigational treatment options.

Main Results:

  • Chronic constipation disproportionately affects the elderly and females.
  • Effective management involves both lifestyle modifications and pharmacologic interventions.
  • Several new medications are under investigation for improved efficacy and safety.

Conclusions:

  • Chronic constipation in the elderly requires a comprehensive management approach.
  • Early diagnosis and appropriate treatment can mitigate quality of life impairments.
  • Ongoing research promises novel therapeutic options for this common condition.