Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oxygen toxicity.

R F Lodato1

  • 1Division of Pulmonary and Critical Care Medicine, University of Texas Health Science Center, Houston.

Critical Care Clinics
|July 1, 1990
PubMed
Summary

Oxygen therapy is a critical medical treatment that can save lives but also cause harm. Careful dosing of oxygen concentration and duration is essential to prevent toxicity and ensure effective oxygenation.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Viagra for impotence of pulmonary vasodilator therapy?

American journal of respiratory and critical care medicine·2001
Same author

Roles of IL-1 and TNF in the decreased ileal muscle contractility induced by lipopolysaccharide.

The American journal of physiology·1999
Same author

Cardiovascular derangement in septic shock and nitric oxide.

Journal of critical care·1996
Same author

Decreased ileal muscle contractility and increased NOS II expression induced by lipopolysaccharide.

The American journal of physiology·1996
Same author

Protective effect of NG-monomethyl-L-arginine against hypotension inducted by combined tumour necrosis factor-alpha and whole body hyperthermia in rats.

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·1996
Same author

Interrelationship of breath components in neighboring breaths of normal eupneic subjects.

American journal of respiratory and critical care medicine·1995

Area of Science:

  • Medicine
  • Pharmacology

Background:

  • Oxygen therapy is a vital clinical tool.
  • Its use presents a paradox: it can be life-saving or life-destroying.

Purpose of the Study:

  • To highlight the critical importance of precise oxygen therapy dosing.
  • To emphasize the need to balance adequate oxygenation with avoiding toxicity.

Main Methods:

  • This study is a review of the principles of oxygen therapy.
  • It focuses on the concept of oxygen dose as concentration x duration.

Main Results:

  • Oxygen therapy's efficacy is directly linked to its "dose."
  • Improper dosing can lead to oxygen toxicity, negating therapeutic benefits.

Conclusions:

  • Clinicians must carefully titrate oxygen therapy.
  • Achieving adequate systemic oxygenation requires meticulous dose management to prevent adverse effects.